Biotech

Sunday, 06 July 2008

Chris Anderson on The End of Theory (Wired/Edge) and the Petabyte Age and Its Impact on Scientific Evolution

Chris Anderson recently wrote a thought-provoking piece in Wired and Edge called The End of Theory in which he focuses on the rise of massive datasets, computational algorithms and correlations (instead of causation) for the next step in scientific evolution. Highly recommended reading.

More importantly, different leading thinkers like Kevin Kelly, Bruce Sterling, Daniel Hillis, George Dyson, Douglas Rushkoff, Jaron Lanier, Stewart Brand and John Horgan respond to the Anderson view in this post on Edge analyzing the pros and cons of The End of Theory article. Below some quotes by Anderson and his critics.

In my view, correlation might boost useful science in the sense of working or realistic correlations. Nonetheless, in most disciplines intuition, creativity, asking good questions (perspectives/frames !), understanding, models and theory still have a clear value add, albeit for social / sharing reasons on top of a deeper understanding of the why of natural or social phenomena. Additionally, the reasoning of Chris Anderson is relevant for the rise of the mobile internet and its ubiquitous computing role in the near future. All these real-time mobile sensors might boost correlations and predictive capabilities to a certain degree while still acknowledging the power of Black Swans. Furthermore, Andersons' view seems to resonate with the Internet Scenario and Digital Gaia Scenario within the Singularity according to Vernor Vinge in which the continuing profileration and advancement of the internet will give rise to posthuman sense of consciousness as its too complex to contemplate. Finally, the role of the Semantic Web/Web 3.0 is interesting in the light of Andersons' reasoning. He seems to disagree with the benefits of the meaning and top-down structures of the Semantic Web. It would be great to see the responses of Tim Berners Lee and Nova Spivack to the Anderson piece. 

"All models are wrong, but some are useful. So proclaimed statistician George Box 30 years ago, and he was right. But what choice did we have? Only models, from cosmological equations to theories of human behavior, seemed to be able to consistently, if imperfectly, explain the world around us. Until now. Today companies like Google, which have grown up in an era of massively abundant data, don't have to settle for wrong models. Indeed, they don't have to settle for models at all.

Sixty years ago, digital computers made information readable. Twenty years ago, the Internet made it reachable. Ten years ago, the first search engine crawlers made it a single database. Now Google and like-minded companies are sifting through the most measured age in history, treating this massive corpus as a laboratory of the human condition. They are the children of the Petabyte Age.

Chris Anderson seems to think computers will reduce science to pure induction, predicting the future based on the past. This method of course can't predict black swans, anomalous, truly novel events. Theory-laden human experts can't foresee black swans either, but for the foreseeable future, human experts will know how to handle black swans more adeptly when they appear.

Just because we remove the limits and biases of human narrativity from science, does not mean other biases don't rush in to fill the vacuum.

It is clear to me that while numerical simulation and computation are welcome tools, they are helpful only when they are used by good scientists to enhance their powers of creative reasoning. One rarely succeeds by “throwing a problem onto a computer”, instead it takes years and even decades of careful development and tuning of a simulation to get it to the point where it yields useful output, and in every case where it has done so it was because of sustained, creative theoretical work of the kind that has been traditionally at the heart of scientific progress."

Sunday, 29 June 2008

Our Technological Future: Special on the Singularity by Vernor Vinge

IEEE Spectrum has a fantastic special edition on the Singularity just released in June 2008.
In this post on the many faces of the Singularity and our human and technological future are some remarkable quotes by Vernor Venge. For all readers who are into deep future, Metaverse, Multiverse and Augmented Reality. Highly recommended as this is in my view mind-expanding and blowing material !

"I expect the singularity will come as some combination of the following:   
1. The AI Scenario: We create superhuman artificial intelligence (AI) in computers.
2. The IA Scenario: We enhance human intelligence through human-to-computer interfaces—that is, we  achieve intelligence amplification (IA).
3. The Biomedical Scenario: We directly increase our intelligence by improving the neurological operation of our brains.
4. The Internet Scenario: Humanity, its networks, computers, and databases become sufficiently effective to be considered a superhuman being.
5. The Digital Gaia Scenario: The network of embedded microprocessors becomes sufficiently effective to be considered a superhuman being.

Several of the essays discuss the plausibility of mind uploads and consequent immortality for “our digitized psyches,” ideas that have recently appeared in serious  nonfiction, most notably Ray Kurzweil's The Singularity Is Near. As with nanotechnology, such developments aren't prerequisites for the singularity. On the other hand, the goal of enhancing human intelligence through human-computer interfaces (the IA Scenario) is both relevant and in view. Today a well-trained person with a suitably provisioned computer can look very smart indeed. Consider just a slightly more advanced setup, in which an Internet search capability plus math and modeling systems are integrated with a head‑up display. The resulting overlays could give the user a kind of synthetic intuition about his or her surroundings. At a more intimate but still noninvasive level, DARPA's Cognitive Technology Threat Warning System is based on the idea of monitoring the user's mental activities and feeding the resulting analysis back to the user as a supplement to his or her own attention. And of course there are the researchers working with direct neural connections to machines. Larger numbers of implanted connections may allow selection for effective subsets of connections. The human and the machine sides can train to accommodate each other.

Brooks suggests that the singularity might happen—and yet we might not notice. Of the scenarios I mentioned at the beginning of this essay, I think a pure Internet Scenario—where humanity plus its networks and databases become a superhuman being—is the most likely to leave room to argue about whether the singularity has happened or not. In this future, there might be all-but-magical scientific breakthroughs. The will of the people might manifest itself as a seamless transformation of demand and imagination into products and policy, with environmental and geopolitical disasters routinely finessed. And yet there might be no explicit evidence of a superhuman player.

A singularity arising from networks of embedded microprocessors—the Digital Gaia Scenario—would probably be less deniable, if only because of the palpable strangeness of the everyday world: reality itself would wake up. Though physical objects need not be individually sapient, most would know what they are, where they are, and be able to communicate with their neighbors (and so potentially with the world). Depending on the mood of the network, the average person might notice a level of convenience that simply looks like marvelously good luck. The Digital Gaia would be something beyond human intelligence, but nothing like human. In general, I suspect that machine/network life-forms will be faster, more labile, and more varied than what we see in biology. Digital Gaia is a hint of how alien the possibilities are."

Sunday, 23 March 2008

Craig Venter on Synthetic Biology (LongNow Foundation Presentation)

One of the most exciting new scientific topics around: Synthetic Biology. If this field keeps on growing we are in my view experiencing a more revolutionary trajectory the coming decades relative to the internet (online and mobile combined). Highly recommended viewing, especially the Q&A. Including some possible solutions for our environmental and resource challenges.

Thursday, 07 February 2008

Richard Dawkins, Craig Venter and John Brockman Video from DLD 2008 on Biotech and Genes

Insightful 1-hour discussion on biotech and genetics by two of the leading experts in our world.


Link: sevenload.com

Thursday, 28 June 2007

On BANG Convergence and Three Other Key Value Drivers in the Coming Decades

Global Business Network is one of my favorite sources. To me Peter Schwartz, Stewart Brand and Eamonn Kelly are leading thinkers. In this short PDF document Eamonn Kelly - author of the highly acclaimed (futuristic) book Powerful Times - sheds some light on four key drivers of value creation in the coming decades.

The reasons for posting this one are the importance of the Gift Economy (see also the recent remarks by Kevin Kelly, Yochai Benkler and Don Tapscott), the revitalization of the Physical Infrastructure Economy (creative new insight) and most importantly the coming BANG convergence. BANG convergence is bigger than the current Digital Convergence and it relates to Bits, Atoms, Neurons and Genes. This is one of my favorite topics for a very long time as a result of reading the book Complexity. A life changer to me ! After reading this book in 1993, I was lured to the Santa Fe Institute as an inspiring knowledge platform for BANG convergence. It inspired me to read great books by Stuart Kauffman and Ilya Prigogine. And when we watch all those outstanding videos on TED we can see by our own senses why the BANG convergence is the biggest value creator of our times. 

Thursday, 10 May 2007

The Encyclopedia of Life (EOL) : Milestone For All Of Us

Sometimes a new website is launched touching every cell in my body. Encyclopedia of Life (EOL) is such  a website. As a nature lover I believe this is an excellent resource. Thrilling, exciting, moving, inspiring, important, enchanting and above all transcending as this is a milestone for the world, ecology and humanity. Great ! Thanks to E.O. Wilson and TED. The video below shows it all...

"Comprehensive, collaborative, ever-growing, and personalized, the Encyclopedia of Life is an ecosystem of websites that makes all key information about life on Earth accessible to anyone, anywhere in the world. Our goal is to create a constantly evolving encyclopedia that lives on the Internet, with contributions from scientists and amateurs alike. To transform the science of biology, and inspire a new generation of scientists, by aggregating all known data about every living species. And ultimately, to increase our collective understanding of life on Earth, and safeguard the richest possible spectrum of biodiversity."

Wednesday, 18 April 2007

What Is Driving Human History, Competitive Advantage and Our Future ? Some Thoughts From Jared Diamond, Thomas Sowell and William McNeill

Once in a while I give a recap of classic, important articles. In the past, you could see recaps on this blog of God is the Machine by Kevin KellyWhy the Future Doesn't Need Us by Bill Joy, We Are The Web by Kevin Kelly and The Long Tail by Chris Anderson . I saw reread an article on Edge written by Jared Diamond on the differences in human development on different continents. Just like his book (Pulitzer Prize winning) called Guns, Germs and Steel, a terrific overview of the last 13.000 years in human history based on the article.

There is are a few complementary book to Guns, Germs and Steel. One is called Conquests and Conflicts: An International History by Thomas Sowell. Another The Rise of the West: A History of the Human Community by William McNeill. Both highly recommended. McNeill shows us the increasing role of cooperation, community and interdependency. Sowell documents the case of how geography (harbors, arable land, navigable rivers, freedom from monsoons and tropical disease) and ideas/culture (fundamental beliefs and principles widely shared or disseminated) make the world what it is today. The key distinction among human communities is "human capital", the spectrum of individual and collective learned behaviors that produce distinctive patterns of skills and attitudes. The positive form of this capital is based on flexibility/receptivity to cultural transfers and willingness to apply those transfers in different contexts. Sowell shows that these cultures are more competitive and resilient.

While Jared Diamond shows us primarily the (external) environmental factors driving the evolution of human history and development, McNeill and Sowell (also) demonstrate the impact of internal factors like cultures and (cooperative) mindsets driving this evolution. In my view it is a combination of both internal and external factors driving the our human development, complemented by luck. Furthermore, I believe in the earlier days of human development (deterministic) environmental factors were more important than internal factors like culture, ideas and mindset relative to todays' situation. Why ? The human history is all about increasing empowerment and autonomy of individuals, about increasing voluntarism, about using more and more tools en technologies. On top of that, in todays world, geography and other environmental drivers (germs, diseases, guns, etc.) seem to be less relevant for competitive advantage relative to (internal) learning capability. Access to data and information is free and more ubiquitous everyday, now it's more about participation and cooperative skills and attitudes. The only thing that complicates my analysis the (likely) future lack of (external) resources on this planet for everybody (oil/energy, food, water, etc.).

Tools are hacks. Technology changes the evolution of evolution. It is an infinite game according to Kevin Kelly. Agriculture enabled industrial evolution (see quote below from Jared Diamond) which enabled digital revolution (electricity) enabling the current biotech revolution enabling the current/coming nanotech revolution with accellerating speeds. Hockey stick curve stuff (see among others Juan Enriquez on TED in this great presentation). So what do we need to survive and gain an edge in the digital, biotech and nanotech periods ? Geographic advantages (like in Sillicon Valley/Green Valley) ? Environmentally cleaned physical spaces ? Other environmental factors like Jared Diamond describes ? Density of people ? In my view it is nowadays more about a mindset of people: openness, peering, sharing, a global scope and a heartfelt acceptance of diversity in all forms. It is basically internal. This resonates with the (some of the) findings and conclusions of Diamond, McNeill and Sowell. It is increasingly about the soft factors, although not exclusively. See my earlier post on the increasing importance and interrelationships of Identity, Authenticity and Creativity/Innovation. In my view, without these soft, internal factors we will not be able to stop global warming, resource depletion and other problems.

What do YOU think about the above analysis ? Thanks.

"We began by identifying a series of proximate explanations - guns, germs, and so on - for the conquest of the Americas by Europeans. Those proximate factors seem to me ultimately traceable in large part to the Old World's greater number of domesticated plants, much greater number of domesticated animals, and east/west axis. The chain of causation is most direct in explaining the Old World's advantages of horses and nasty germs. But domesticated plants and animals also led more indirectly to Eurasia's advantage in guns, swords, oceangoing ships, political organization, and writing, all of which were products of the large, dense, sedentary, stratified societies made possible by agriculture.

All other things being equal, the rate of human invention is faster, and the rate of cultural loss is slower, in areas occupied by many competing societies with many individuals and in contact with societies elsewhere.  If  this interpretation is correct, then it's likely to be of much broader significance.  The broadest pattern of history - namely, the differences between human societies on different continents - seems to me to be attributable to differences among continental environments, and not to biological differences among peoples themselves. In particular, the availability of wild plant and animal species suitable for domestication, and the ease with which those species could spread without encountering unsuitable climates, contributed decisively to the varying rates of rise of agriculture and herding, which in turn contributed decisively to the rise of human population numbers, population densities, and food surpluses, which in turn contributed decisively to the development of epidemic infectious diseases, writing, technology, and political organization.  In addition, the histories of Tasmania and Australia warn us that the differing areas and isolations of the continents, by determining the number of competing societies, may have been another important factor in human development."

Sunday, 01 April 2007

On Antropocentrism, Parallelism, Evolution and its Impact on Digital Media

Ok, this is highly speculative but here goes anyway.... looking forward to your comments ! It is about three key concepts (parallellism, evolution and antropocentrism) and its impact on digital media.

  • Parallellism: existence of parallel universes, quantum mechanics (possibilities) and dreams. We seem to live multiple lives and in multiple environments.
  • Evolution: evolution of evolution (even the speed of light constant itself changes over time), evolutionary/expanding universe, evolutionary timescale/geology/tectonic plates, evolution of species and Gods Delusion. Static solutions, explanations, values and theories give way to dynamic versions. All is in flux.
  • Antropocentrism: Ptolemeus -> Copernicus (earth-centric became sun-centric view of solar system); evolution of species (we are similar to the apes); dark matter and energy unknown -> we consist of only 5% of the known matter of the universe and extra terrestial intelligence probably exists (Drake's equation). All this implies that increasingly humans are not (!) the center of the universe.

How does this all relate to ICT and digital media ?

Increasing parallelism

  • Serious Gaming (parallel strategic gaming and thinking before implementing IRL)
  • 3D Worlds like Second Life (parallel worlds and identities)
  • Augmented and Mixed Reality (combining physical and digital experiences)

Increasing evolution

  • Hardware, software, services, content and connectivity increasingly become hackable, remixable, reconfigurable, open, dynamic and evolutionary. E.g., Amazon with web scale computing
  • Evolutionary blog posts, articles ; they become conversations, open ended, self correcting and organic documents

Decreasing antropocentrism

  • Bots, AI and machine (besides human) learning within Semantic Web (Web 3.0)
  • The internet of things (pervasive or ubiquitous computing)
  • Robotics
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